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In the early 1990's, the United States' diet craze and mission for thinness found a new drug of choice, Fen-Phen, guaranteed to help users finally lose weight. Two drugs, fenfluramine and phentermine, created the Fen-Phen drink. Fenfluramine works in the body by releasing extra amounts of serotonin, which is the neurotransmitter accountable for feelings of satiety and fullness. Phentermine, a stimulating, would counteract the sleepiness inducing qualities of a surge of serotonin. The particular two drugs had fewer side effects when taken together than when used individually. Although America had not been diet drug crazy considering that the amphetamine use of the 1960's, Fen-Phen seemed like a different sort of weight loss aid. A new 1983 study over the course of four years found that obese patients (those weighing 200 pounds or more) lost 32 pounds on average when taking drug cocktail. This research, along with the medical community's support and users' results, allowed Fen-Phen to dominate the diet drug market in the 1990's.

In 1996 alone, there were 18 million Buy Phenq prescription medications written for Fen-Phen. Us Home Products, the company in charge of manufacturing Fen-Phen, made Fen-Phen available to the public without proper warnings and side effect information. In April 1996, Us Home Products also started out producing Redux, a diet drug that was approved to sell despite a 5-3 vote by a technological panel against its approval. Within a year and a half after its approval, 2. 5 , 000, 000 prescriptions for Redux experienced already been written for dieters.

In 1997, the Mayo Clinic released a report concerning the serious aspect effects and everlasting health problems as a result of the use of Fen-Phen. The most frequent part effect of the medication was heart valve problems, specifically aortic and mitral valves. The heart problems caused by Fen-Phen would require risky heart surgery. Other problems included main pulmonary hypertension, a devastating disease in which blood pressure in the pulmonary artery rises to dangerous levels and creates additional heart failure stress. Soon after, in September 1997, the Meals and Drug Administration (FDA) pulled the diet drugs from the market. By this point, American Home Products had made about one-hundred dollar million from benefiting from00 the diet craze.