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what is lenalidomide medication , N. (2016): Ixazomib (Ninlaro®) in combination with lenalidomide and dexamethasone for the therapy of multiple myeloma (MM). Lenalidomide is similar to thalidomide, a drug which has prompted extreme (presumably fatal) birth defects when used during pregnancy. In Turkey, a generic of Lenalidomide Rivelime® (Deva Medication Ltd, Istanbul, Turkey) has been authorized since 2017.
For patients older than seventy five years of age handled with lenalidomide in combination with dexamethasone, the starting dose of dexamethasone is 20 mg once daily on days 1, 8, 15 and 22 of every 28-day remedy cycle. These medicine ought to NOT be used throughout pregnancy and sufferers should avoid turning into pregnant while taking these medication.
The cumulative 5-12 months incidence of second main malignancies was 6.9 per cent in sufferers who received lenalidomide versus 4.8 per cent in those that did not, giving a major hazard ratio (HR) of 1.55 (P=zero.037). It's a good way to treat a number of myeloma (a cancer which ends up from a progressive blood illness) and lack of purple blood cells within the body or anemia.
That is because Pomalyst's patents defend it till 2024 within the U.S. and 2023 within the EU. Moreover, Celgene has filed for a patent extension that, if awarded, may stretch patent safety by means of 2025 within the United States and beyond 2023 in Europe.
Inform your physician and pharmacist what other prescription and nonprescription medicines, vitamins, nutritional dietary supplements, and natural merchandise you are taking or plan to take. Essentially the most profitable therapeutic within the treatment of MM is Celgene's Revlimid (lenalidomide), which is a stronger molecular analog of thalidomide, which inhibits tumor angiogenesis.
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