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Carbinoxamine; Phenylephrine: (Reasonable) The therapeutic effect of phenylephrine may be elevated in affected person receiving corticosteroids, reminiscent of hydrocortisone. In sufferers with extreme illness, and particularly in adults, phototherapy, methotrexate (MTX), sixty three , 64 azathioprine, cyclosporine, and mycophenolate mofetil four have been used with success.
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Carbinoxamine; Phenylephrine: (Reasonable) The therapeutic effect of phenylephrine may be elevated in affected person receiving corticosteroids, reminiscent of hydrocortisone. In sufferers with extreme illness, and particularly in adults, phototherapy, methotrexate (MTX), sixty three , 64 azathioprine, cyclosporine, and mycophenolate mofetil four have been used with success.
Topical immunomodulators equivalent to tacrolimus and cyclosporine A additionally signify choices for lengthy-term therapy of those sufferers, displaying side effects which can be generally transient and with no rebound effect following discontinuation of the drug( 11 ). Nonetheless, these drugs are very costly in Brazil, and in some cases, recurrent allergy crises happen even while using them.
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