Thalidomide is efficient within the therapy of a number of myeloma. In each research, the REVLIMID maintenance dose was 10 mg as soon as day by day on days 1-28 of repeated 28-day cycles, could be increased to fifteen mg as soon as each day after 3 months within the absence of dose-limiting toxicity, and therapy was to be continued till disease development or affected person withdrawal for one more purpose.
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Few opposed events had been reported throughout maintenance therapy; 88% of the patients accomplished induction remedy and 70% completed maintenance therapy as deliberate ( Figure 1 ).
side affects of lenalidomide of second primary tumors was low and, in three of the 4 cases, early indicators of the tumor had been already present at examine entry.
For imatinib mesylate, the generic equivalent for Gleevec, the share of costs above the catastrophic protection threshold is lower (43%) because enrollees taking this drug don't obtain a manufacturer low cost within the protection hole and therefore would incur greater out-of-pocket prices under the catastrophic protection threshold.