A high SaFA intake appears to be improve gut motility.
Jamie Scott covers a newly published study...from the page: "There was an unpublished pilot study that was completed at Monash University, Melbourne, Australia, that I was sent a while back and that I have made reference to before, where the authors believed that non-coeliac gluten intolerance does exist. This study has now been published..."
Food Chem Toxicol. 2009 Dec;47(12):2899-905. Epub 2009 Mar 13.Probabilistic modelling of exposure doses and implications for health risk characterization: glycoalkaloids from potatoes.Ruprich J, Rehurkova I, Boon PE, Svensson K, Moussavian S, Van der Voet H, Bosgra S, Van Klaveren JD, Busk L.NIPH - National Institute of Public Health, Prague, CHFCH Brno, Palackeho 3a, 61242 Brno, Czech Republic. jruprich@chpr.szu.czAbstractPotatoes are a source of glycoalkaloids (GAs) represented primarily by alpha-solanine and alpha-chaconine (about 95%). Content of GAs in tubers is usually 10-100 mg/kg and maximum levels do not exceed 200 mg/kg. GAs can be hazardous for human health. Poisoning involve gastrointestinal ailments and neurological symptoms. A single intake of >1-3 mg/kg b.w. is considered a critical effect dose (CED). Probabilistic modelling of acute and chronic (usual) exposure to GAs was performed in the Czech Republic, Sweden and The Netherlands. National databases on individual consumption of foods, data on concentration of GAs in tubers (439 Czech and Swedish results) and processing factors were used for modelling. Results concluded that potatoes currently available at the European market may lead to acute intakes >1 mg GAs/kg b.w./day for upper tail of the intake distribution (0.01% of population) in all three countries. 50 mg GAs/kg raw unpeeled tubers ensures that at least 99.99% of the population does not exceed the CED. Estimated chronic (usual) intake in participating countries was 0.25, 0.29 and 0.56 mg/kg b.w./day (97.5% upper confidence limit). It remains unclear if the incidence of GAs poisoning is underreported or if assumptions are the worst case for extremely sensitive persons.
Food Chem Toxicol. 2008 Aug;46(8):2837-40. Epub 2008 Jul 9.
A human dietary risk assessment associated with glycoalkaloid responses of potato to Colorado potato beetle defoliation.
Dinkins CL, Peterson RK.
Department of Land Resources and Environmental Sciences, Montana State University, Bozeman, Montana 59717-3120, USA.
Abstract
A quantitative human dietary risk assessment was conducted using the glycoalkaloid concentrations measured from tubers of plants defoliated by Colorado potato beetles and undefoliated (control). There was a significantly greater production of glycoalkaloids for defoliated plants compared to control plants for both skin and inner tissue of tubers. The dietary risk posed to different human subgroups associated with the consumption of potatoes was estimated for the 50th, 95th, and 99.9th percentile US national consumption values. Exposures were compared to a toxic threshold of 1.0mg/kg body weight. Defoliation by Colorado potato beetles increased dietary risk by approximately 48%. Glycoalkaloid concentrations within the inner tissue of tubers, including undefoliated controls, exceeded the toxic threshold for all human subgroups at less than the 99.9th percentile of exposure, but not the 95th percentile.
PMID: 18614268 [PubMed - indexed for MEDLINE]